IL4 and tuberculosis: Immunological factors induced by Th2 lymphocytes: IL-4: two trials [59], [62] reported the level of IL-4 and both of them showed a significant difference between the immunotherapy group and control group (data not shown).The immunotherapy had significant effect of reducing the grossly raised level of IL-4 on admission in newly diagnosed TB patients after one [59], or one, two and three [62] month(s) administration (P<0.001 in both studies), suggesting that the immunotherapy helped to reduce the influence of Th2 to the benefit of the patients.