CD226 and neoplasm: Inclusion of an anti-TGF-β antibody into the co-culture between IL-15 stimulated NK cells and tumour cells revealed that TGF-β blockade restored NK cell effector function (Figure 1A, B and Figure S2) and that this was associated with a restoration of NKp30 expression at the cell surface and increases in both DNAM-1 and NKG2D molecules (Figure 1C).