Of note, adoptive T cell transfer of CD8 T cells from either CVB3-infected β5i/LMP7+/+ and β5i/LMP7-/- mice into β5i/LMP7-/- recipient mice resulted in a slightly milder acute disease than in non-transfected mice (respective myocarditis score from CVB3-infected donor mice are shown in the middle panel of Fig. 5D). Here, PSMB8 is linked to myocarditis.