The KLK5 expression of the benign tissue specimens ranged between 0.035-1380.4×103 KLK5 mRNA copies/103 HPRT1 mRNA copies (c/Kc), while the expression in the tissue specimens obtained by the breast cancer patients varied between 0.035-19.6x103 c/Kc. The gene discussed is HPRT1; the disease is breast carcinoma.