Nevertheless, the clinical utilities of GP73 are still controversial: Mao et al. [76] showed that GP73 was an accurate serum marker for detection of HCC and recurrence after surgery, whereas Yamamoto et al. and Ozkan et al.[77,78] showed that it was not useful in the diagnosis of HCC, in monitoring treatment response, or in prognosis. Here, GOLM1 is linked to hepatocellular carcinoma.