AFP and Cirrhosis: The GlycoHCC test, using the log ratio of a branch alpha (1,3)-fucosylated triantennary glycan (elevated in HBV patients with cirrhosis) to a bisecting core alpha(1,6)-fucosylated biantennary glycan (elevated in HBV patients with HCC), shows similar sensitivity and specificity to that of AFP in screening HCC from patients with cirrhosis[64].