HLA-B and toxic epidermal necrolysis: In the primary analyses, SJS/TEN cases were significantly more likely to carry HLA-B*5801 allele compared with both matched-control (OR 96.60, 95%CI 24.49-381.00, p < 0.001) and population-control (OR 79.28, 95%CI 41.51-151.35, p < 0.001) (Figure 2).