TP53 and colorectal carcinoma: Of 28 TP53 mutations observed, 15 (53.6%) were missense and 13 (46.4%) were FS and nonsense, which was significantly different from CRC mutations listed in UMD, where missense mutations were highly predominant (81% missense, 19% FS and nonsense, P = 0.0005, X2 test).