BRCA1 and hemophilia: In genetics, this method has been applied to BRCA1/2 hereditary breast cancer [30], cystic fibrosis [31], haemophilia [32], the instability of microsatellites [33], the rearrangement of heavy chain genes in lymphomas [34], the prenatal diagnosis of B-thalassaemia [35], analysis of DNA methylation [36], the identification of bacterial species [37,38], and other applications.