These include: 1) markers of tumor proliferation and cell cycle regulation (mitosin, telomerase, Cyclin D1, p21, IGFBP-rP1), 2) intercellular interaction (P cadherin, calgranulin, psoriasin), 3) extracellular matrix regulation (urokinase plasminogen activator system, metalloproteinase and its inhibitors) and 4) angiogenesis. The gene discussed is S100A7; the disease is neoplasm.