Close inspection of the 3D plot shows that AK1C3 at a point (40.8, 0, 39.1), AK1C1 at a point (39.0, 0, 37.4), AL1A1 at a point (8.75, 2.6 × 10-5, 11.8) and CD44 antigen precursor (CD44) at a point (5.56, 0, 5.27) are very near or on the x-z plane with convincingly low p-values (3.9 × 10-10, 9.6 × 10-10, 6.1 × 10-4, and 0.021, respectively) from LCNEC vs. SCLC comparisons and thus specific to LCNEC. Here, CD44 is linked to large cell neuroendocrine carcinoma.