To address the specificity of such alteration of miR-146a, miR-125b and miR-150 in the presence of poly Q aggregates, mutated exon1 of HTT gene that translated to N-terminal HTT with 83 Q was exogenously expressed in four different cell lines viz., Neuro2A (mouse neuroblastoma cell line), STHdhQ7/HdhQ7 (mouse sriatal cells having two copies of full length HTT with 7Q), SH-SY5Y (human neuroblastoma cell line) and HeLa cells (human cells derived from cervical tumours) and the expression of twenty two miRNAs were studied in these cell models (Table S1). The gene discussed is HTT; the disease is uterine cervix neoplasm.