MMP9 and coronary artery disorder: In cases where association was attenuated, the most disparate finding when omitting the subgroup in HW disequilibrium was found for the pharmacogenetic effect of the MMP9 R668Q variant on combined CHD when comparing chlorthalidone to amlodipine: for the full group modeled recessively, the ratio of hazard ratios was 0.64 (P = 0.04), whereas it was 0.71 (P = 0.13) when omitting the White-Hispanic group.