It has been reported that GLP-1 receptors are expressed in both heart and coronary vasculature and activation of GLP-1 receptors by agonists results in a wide range of cardiovascular effects such as cardioprotection against myocardial ischemia-reperfusion injury both ex vivo[4]–[7] and in vivo[5]. Here, GLP1R is linked to myocardial ischemia.