TNF and Hyperglycemia: The main idea of the current research study was to examine the ability of T2DM-induced hyperglycemia in enhancing the pathogenicity of NAFLD by induction of oxidative stress (hydrogen peroxide and malondialdehyde) and releasing of inflammatory mediators (TNF-α and IL-6) in absence of liver damage as confirmed by the presence of normal liver function tests (LFTs).