The highest PCC values, including the anti-correlation between PKDM10B and MLL1 (PCC = −0.62), and correlation in KDM5B–ASH1 (PCC = 0.82) and KDM2A–MLL1 (PCC = 0.74) pairs, were revealed in colon cancer cell lines. The gene discussed is KMT2A; the disease is malignant colon neoplasm.