Furthermore, a number of shared epistatic genes in the two populations (Table S2) suggested links between SUA levels and various diseases such as autism (CNTNAP2, POU6F2, MYO1D), schizophrenia and bipolar disorder (ERC2, ROBO1, ROBO2, CNTNAP2, GRM7, SYNE1, CNTN5, ANKS1B), Alzheimer's disease (EPHA4, CNTN4, ADCY8, PCSK5, CUBN, SORCS1, RORA, GRIN2A), Parkinson's disease (DLG2), sclerosis (RGS7, CNTN4, IGF2R, SH3GL2, GPC5, GPC6, GRIN2A, MYH9), and diabetes (CD69, PTPRD, SORCS1, PREX1). Here, GRM7 is linked to bipolar disorder.