HLA-DRB1 and coinfection: In the final model, increased age by year, BMI <16.0, HIV co-infection and the number of HLA-DRB1*0701 alleles showed significant association with QFT-IT negativity (OR = 1.04 [95% CI, 1.01–1.07], 5.42 [95% CI, 1.48–19.79], 6.38 [95% CI, 1.78–22.92] and 5.09 [95% CI, 2.31–11.22] respectively) (table 5).