This antibody, which recognized the predicted protein of approximately 120 kD in a western blotting experiment (Figure 1A), detected high levels of SH3PXD2B in several human tumor cell lines e.g. in HeLa, 293T, the acute B-cell leukemia line REH, the erythroleukemia cell line TF1 and the A2058 melanoma. The gene discussed is SH3PXD2B; the disease is neoplasm.