Whereas in the dose-dependent experiments IFI44L showed similar selectivity and induction levels to the MX1, IFIT1 appeared to be more selective and induced to a higher degree compared to the MX1. IFIT1 encodes a protein that is rapidly induced in response not only to viral infections but also non-viral stimuli such as LPS, IL-1 and TNFα [33], [34], and may be involved in cell apoptosis via interaction with the eukaryotic elongation factor-1A (eEF1A)[35]. The gene discussed is TNF; the disease is viral infectious disease.