Winder and colleagues [14] studied 16 MDS patients (4 RA, 3 RARS, 3 RCMD, and 6 RAEB) 13 of them chronically transfused and found undetectable or inappropriately low urinary hepcidin in most of them. The gene discussed is HAMP; the disease is myelodysplastic syndrome with ring sideroblasts.