Given that CXCR4 has been linked with the metastasis of various cancers and CXCR4 expression has been correlated with poor prognosis and poor overall patient survival [57], CXCR4 appears an ideal therapeutic target for the investigation of novel therapeutic interventions for the prevention of metastatic cancer. This evidence concerns the gene CXCR4 and metastatic malignant neoplasm.