INS and hypertensive disorder: There was no significant association between developing hypertension and baseline body mass index (P = 0.46), insulin dose (P = 0.14), level of education (P = 0.30), socioeconomic status (P = 0.32), alcohol abuse (P = 0.09), blood total cholesterol levels (P = 0.23), total cholesterol/HDL-C (P = 0.16), glycosylated hemoglobin values (P = 0.11), or being depressed (P = 0.20).