VEGFA and neuroblastoma: Several experimental therapeutic strategies including VEGF inhibitors, antibodies directed against VEGF or against its receptors, soluble truncated receptors, introduction of anti-sense VEGF RNA, development of dominant-negative VEGF mutants and agents interfering directly with VEGF signal transduction have been emerged to target the interaction of VEGF with its receptors and thereby to suppress growth of neuroblastoma [54].