Previous experimental studies showed a plateau in expression of ICAM-1 by endothelial cells after TNF-α activation between days 1-3 [24], and after the stroke onset a persistency in soluble ICAM-1 levels on days 1, 3 and 14 [17] was detected; our follow-up data on day 3 is in line with these findings. The gene discussed is TNF; the disease is stroke disorder.