A recent study was undertaken to determine plasma RBP4 and adiponectin levels in subjects with cerebral infarction and showed that adiponectin and hypertension were independent factors contributing to cerebral infarction; moreover, it has been shown that plasma RBP4 levels in the subjects with cerebral infarction were significantly greater than those in control subjects [10]. This evidence concerns the gene RBP4 and cerebral infarction.