The following phenotypic features characterized 4 of the 6 samples from which NS generated and 3 of the 9 samples from which AC generated: high cell density, high number of mitoses, a Ki-67/MIB-1 labeling index (LI) between 25% and 30%, circumscribed necroses with pseudo-palisading, high vessel density, and perivascular cuffings of tumor cells (Figure 1). The gene discussed is MKI67; the disease is neoplasm.