SNP rs1128127 is a missense mutation (Ala211Val) within the Der1-like domain family gene Derl3. Individuals with a homozygous AA genotype (encoding 211Val) at this locus were significantly less likely to clear drug resistant infections than those who were homozygous GG or heterozygous (OR = 0.77 [95%, CI: 0.45 - 0.99], P = 0.05). This evidence concerns the gene DERL1 and infection.