STK11 and hereditary nonpolyposis colon cancer: Familial adenomatous polyposis syndromes [3,4], hereditary non-polyposis colorectal cancer [5-8], and other polyposis syndromes which increase the incidence of colorectal cancer including Peutz Jegher's syndrome, familial juvenile polyposis, and hereditary mixed polyposis syndrome, are linked to mutations in LKB1, STK11, SMAD4, PTEN, E-cadherin, cyclin D1, and transforming growth factor β receptors [2].