CD86 and central nervous system cancer: This has been confirmed by in vitro analyses showing induction of MHC class II molecules, CD80, CD86 and IL-12 in co-culture experiments of DCs and PDT-treated mouse tumour cells (Gollnick et al, 2002; Jalili et al, 2004) or DCs and acid-eluted material from PDT-treated C6 rat glioma cells (Shixiang et al, 2010).