IFNG and neoplasm: From the efficacy of PDT-generated vaccines, which was superior compared to vaccines generated using UV or ionising irradiation (Gollnick et al, 2002; Korbelik and Sun, 2006), and from the efficacy of intratumourally injected DCs following PDT (Jalili et al, 2004; Saji et al, 2006; Sur et al, 2008) as well as from increased frequencies in IFNγ-secreting cells and the generation of tumour-specific CTL in the treated animals reported by others, it can be concluded that DCs have undergone maturation owing to PDT treatment of the tumour cells in these studies as well.