CR1 and carcinoma: CR-1 is not usually expressed in adult normal tissues, whereas high expression of CR-1 transcript and/or protein has been observed in different human carcinomas, including breast, colon, stomach, pancreas, lung, ovary, cervix and testis, and in leiomyosarcomas of the uterus (Normanno et al, 2001; Bianco et al, 2005; Strizzi et al, 2007).