To investigate the impact of lymphopenia driven proliferation, we compared s.c. tumor growth in mice after vaccination with either mGC8 alone or mGC8 combined with an injection of GM-CSF in IFA, or the latter vaccination following treatment with cyclophosphamide and reconstitution with naïve splenocytes (LRAST, Figure 2A). The gene discussed is CSF2; the disease is neoplasm.