IFNG and neoplasm: Unexpectedly, application of cyclophosphamide and reconstitution with naïve syngeneic splenocytes prior to the tumor vaccination with GM-CSF (LRAST) did not further increase but rather tended to decrease the tumor-specific immune response in vitro as determined by tumor-specific IFN-γ secretion and specific lysis of mGC8 tumor cells by TVDLN cells.