Furthermore, our group has previously shown that VLPs from murine polyomavirus (MPyVLPs) carrying the breast cancer antigen Her2 (Her2-MPyVLPs) can protect mice from outgrowth of the Her2-expressing murine tumor cell D2F2/E2, as well as spontaneous tumor formation in transgenic BALB-neuT mice [29]. This evidence concerns the gene ERBB2 and neoplasm.