CD4 and cryohydrocytosis: However, HCV core antigen level was negatively correlated with CD4+ T cell counts and anti-HCV antibody response (S/CO ratio) was positively correlated with CD4+ T cell counts in HIV seropositive CHC patients with CD4+ T cell counts less than 1000/μl, while no correlation was found between HCV RNA level and CD4+ T cell count.