Specifically for pneumococcal bacteremia 15 tagSNPs in eight genes (CD46, SFTPA1, SFTPD, ILIR1, IL4, IL12B, IL18, and MYD88) and seven tagSNPs in seven genes (MBL2, SFTPD, IL1B, ILIR1, IL4, and PTAFR) are associated with cases of pneumococal bacteremia compared to controls in EA and AA, respectively (Table S3). Here, IL18 is linked to pneumococcal bacteremia.