ALL samples are characterized by a decrease of anti-oxidants (for instance, a decrease of catalase and superoxide dismutase activities [38], [39]) and a sustained oxidative stress (due to a low NAD(P)H:quinone oxidoreductase 1 activity, known to attenuate oxidative stress [40], and/or aggressive chemotherapy protocols [38]). The gene discussed is CAT; the disease is acute lymphoblastic leukemia.