Interestingly, both CML patient groups had significantly larger proportion of CD45RO-positive T-cells, which are antigen encountered memory cells (58% in IFN-ON group and 74% in IFN-OFF group vs. 44% in healthy volunteers, p = 0.0059)(figure 1D, Table S1). The gene discussed is IFNA1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.