In addition, Foxy5, a Wnt5a-derived hexapeptide (the same peptide as Box5 but differently modified) that can mimic Wnt5a-induced activities in malignant melanoma and in breast cancer cells [55], was also able to potentiate the neurotoxicity of Aβ/H2O2 (Fig. 4D). The gene discussed is WNT5A; the disease is melanoma.