However, once a type 2 LCL is eventually established (up to 4 months after infection, with a delay of approximately 3 months compared to type 1 LCLs), LMP-1 and CXCR7 expression levels are similar to those detected in type 1 LCLs (Figure 3 B and C), confirming that those genes are essential for long-term proliferation of EBV-LCLs. This evidence concerns the gene ACKR3 and infection.