FLT1 and neoplasm: Accordingly, after completion of chemoradiotherapy higher VEGFR-1/-2 expression levels (p = 0.025; p = 0.063) were observed in tumour tissue as compared to healthy mucosa at time of surgery, whereas no differences in gene expression levels of VEGFR-1 and -2 were observed in tumour samples before and after neoadjuvant radiotherapy (Figure 1).