Interestingly, our analyses revealed that this is also the case here, with the DISC1 pathway proteins clearly exhibiting a higher abundance of intrinsically disordered residues, compared to the human proteome , as well as a set of brain and schizophrenia-related protein sequences (p = 0.018; 0.013 and 0.0098, respectively) (Figure 1, panel B). Here, DISC1 is linked to schizophrenia.