We observed a similar pattern of gene regulation upon FGF receptor inhibition in HCT116 colon cancer cells (which displayed loss of spindle form upon FGFR3 RNA interference or FGF receptor inhibition, see Fig. S2, S3), implicating a conserved role of this gene cluster downstream of the FGF receptors (Fig. S7). The gene discussed is FGFR3; the disease is colonic neoplasm.