RUNX1 and leukemia: Hints about an indirect inhibition, although in different cell types and differentiation context, exist: In Landry et al. [63], RUNX1 has been identified as a direct target of SCL in the yolk sac, while Tokita et al. [64] showed that the leukemia-inducing fusion protein RUNX1/EVI1 inhibits C/EBP function in LG-3 cells.