APOE and breast cancer: For example, GWAS have indicated that alleles in the FGFR2 gene are associated with sporadic postmenopausal breast cancer [1]; that five loci are associated with breast cancer including the plausible causative genes FGFR2, TNRC9, MAP3K1, and LSP1[2]; and that GAB2 alleles may modify Alzheimer's risk in APOE carriers [3].