Low CN of KIAA1267 (coding for an uncharacterised protein) and UGT2B28 (encoding uridine diphosphate glucuronosyltransferase (UGT) 2 family, polypeptide B28), and high CN of ADAM3A (encoding a disintegrin and metalloproteinase domain 3A), occurred more frequently (> 30%) in AD patients. Here, ADAM3A is linked to Alzheimer disease.