Examples of Duane retraction syndrome with systemic findings and a known genetic basis include dominant mutation in Sal-like 4 (SALL4; with radial ray and/or renal malformation), dominant mutation in Sal-like 1 (SALL1; with renal, anal, and/or auricular malformation), or recessive mutation in homeobox A1 (HOXA1; with inner ear and cerebrovascular malformation and autism) [14]. The gene discussed is SALL4; the disease is Duane retraction syndrome.