Spastic Ataxia Charlevoix-Saguenay (SACS) is the gene most frequently associated with ARSACS (cytogenetic location: 13q12; molecular location on chromosome 13: base pairs 23,902,964 to 24,007,840). This evidence concerns the gene SACS and Autosomal recessive spastic ataxia of Charlevoix-Saguenay.