TNFRSF1B and type 2 diabetes mellitus: We then investigated the effect of TNFRSF1B polymorphisms on quantitative metabolic traits related to type 2 diabetes viz BMI, WHR, HbA1c, fasting glucose, insulin, C-peptide, total cholesterol, TG, HDL-C, LDL-C, urea, uric acid and creatinine (Table 4).