Small cell lung carcinoma is characterized by high invasive and metastatic capacity, a typical feature of MET-activated tumour models (Comoglio and Trusolino, 2002; Danilkovitch-Miagkova and Zbar, 2002) and previous studies suggest a role for MET in SCLC (Maulik et al, 2002; Jagadeeswaran et al, 2007; Ma et al, 2007). The gene discussed is MET; the disease is small cell lung carcinoma.