TNF and metabolic dysfunction-associated steatotic liver disease: The general association between NAFLD and CVD was established by the fact that the liver is involved in regulating/secreting numerous CVD risk factors, notably the cytokine tumor necrosis factor-alpha (TNF-α), an acute-phase protein CRP, glucose, lipoproteins, coagulation factors (plasminogen activator inhibitor-1), and a substance which increases blood pressure (angiotensin II) [7].