DICER1 and neoplasm: Furthermore, the lower metastatic propensity of SW480 cells as compared with SW620 human colon cancer cells, both derived from the primary tumor and a metastasis of the same patient, respectively [96], was associated with a lower level of expression of miR-103-1 and miR-103-2, two miRNAs that induce epithelial-to-mesenchymal transition by targeting Dicer1 transcripts [60].